Diabetic cardiomyopathy (DCM) Toys is a serious complication of type 1 and type 2 diabetes, which leads to the aggravation of myocardial fibrosis, disorders involving systolic and diastolic functions, and increased mortality of patients with diabetes through mechanisms such as glycolipid toxicity, inflammatory response, and oxidative stress.Ferropt
The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis
Abstract The development of granulomas with central necrosis harboring Mycobacterium tuberculosis (Mtb) is the hallmark of human tuberculosis (TB).New anti-TB therapies need to effectively penetrate the cellular and necrotic compartments of these lesions and reach sufficient concentrations to eliminate Mtb.BTZ-043 is a novel antibiotic Laundry Tin
A Review of Two Decades of In Situ Conservation Powered by Public Aquaria
The Top / Bottom Oven Element European Union of Aquarium Curators (EUAC) boasts a membership of 150 dedicated individuals, standing as a vital cornerstone within the European public aquarium community.Since 2004, the EUAC Conservation Fund has granted over a quarter of a million euros to approximately 50 conservation projects spanning the globe.The
Persistent T cell-mediated immune responses against Omicron variants after the third COVID-19 mRNA vaccine dose
IntroductionThe prime-boost COVID-19 mRNA vaccination strategy has proven to be effective against severe COVID-19 disease and death.However, concerns have been raised due to decreasing neutralizing antibody levels after COVID-19 vaccination and due to the emergence of new immuno-evasive SARS-CoV-2 variants that may require additional booster vaccin